Dose-response Relationship of Radiation-induced Leukemia
Surveys targeting atomic bomb survivors made it clear that the dose-response relationship of leukemia, excluding chronic lymphocytic leukemia and adult T-cell leukemia, is quadric, and the higher an exposure dose is, the more sharply risks increase, showing a concave dose-response relationship (the linear quadratic curve in the figure). On the other hand, risks posed by low-dose exposure are considered to be lower than estimated based on a simple linear dose-response model.
In the figure above, black dots show excess relative risks depending on levels of bone marrow absorbed doses and the black line shows excess relative risks based on a linear quadratic model.
(Related to p.93 of Vol. 1, "Relative Risks and Attributable Risks")
- Included in this reference material on March 31, 2013
- Updated on February 28, 2018