Health & Chemicals

Strategic Programs on Environmental Endocrine Disruptors '98 (SPEED '98) - Table-3

Table-3: Chemicals Suspected of Having Endocrine Disrupting Effects

SubstancesEnvironmental InvestigationUseRestrictions
1.
Dioxins and furans		 (Unintended product) Air Pollution Law, Waste Disposal and Public Cleaning Law, POPs
2.
Polychlorinated biphenyl
(PCB)		 Heat medium, non-carbon paper, electric product Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1974, stopped production in 1972, Water Pollution Control Law, Marine Pollution Prevention Law, Waste Disposal and Public Cleaning Law, Environmental Quality Standards for Groundwater, Soil Pollution, and Water Pollutants, POPs
3.
Polybromobiphenyl (PBB)		 Fire retardant
4.
Hexachlorobenzene (HCB)		 Bactericide, organic synthetic raw material Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1979, unregistered in Japan, POPs
5.
Pentachlorophenol (PCP)		 Antiseptic, herbicide,
bactericide		 Lapsed in 1990, Water-pollutant Agricultural Chemicals, Poisonous and Deleterious Substances Control Law
6.
2,4,5-Trichlorophenoxyacetic acid		 Herbicide Lapsed in 1975, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
7.
2,4-Dichlorophenoxyacetic acid		 Herbicide Registered
8.
Amitrole		 Herbicide, disperse dye,
hardener for resins		 Lapsed in 1975, Food Sanitation Law
9.
Atrazine		 Herbicide Registered
10.
Alachlor		 Herbicide Registered, Marine Pollution Prevention Law
11.
Simazine (CAT)		 Herbicide Registered, Water Pollution Control Law, Environmental Quality Standards for Groundwater, Soil Pollution, and Water Pollutants, Waste Disposal and Public Cleaning Law, Waterworks Law
12.
Hexachlorocyclohexane,
Ethyl parathion		 Insecticide, Hexachlorocyclohexane lapsed and banned sales in 1971, ethyl parathion lapsed in 1972
13.
Carbaryl		 Insecticide Registered, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
14.
Chlordane		 Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1968, Poisonous and Deleterious Substances Control Law, POPs
15.
Oxychlordane		 Chlordane metabolite
16.
trans-Nonachlor		 Insecticide Nonachlor unregistered in Japan, heptachlor lapsed in 1972
17.
1,2-dibromo- 3-chloropropane		 Insecticide Lapsed in 1980
18.
DDT		 Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed and banned sales in 1971, Food Sanitation Law, POPs
19.
DDE and DDD		 Insecticide (DDT metabolite) Unregistered in Japan
20.
Kelthane (Dicofol)		 Acaricide Registered, Food Sanitation Law
21.
Aldrin		 Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1975, Soil-persistent Agricultural Chemicals, Poisonous and Deleterious Substances Control Law, POPs
22.
Endrin		 Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1975, Crop-persistent Agricultural Chemicals, Poisonous and Deleterious Substances Control Law, Food Sanitation Law, POPs
23.
Dieldrin		 Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1975, Soil-persistent Agricultural Chemicals, Poisonous and Deleterious Substances Control Law, Food Sanitation Law, Harmful Substance Containing Household Products Control Law, POPs
24.
Endosulfan (Benzoepin)		 Insecticide Poisonous and Deleterious Substances Control Law, Water-pollutant Agricultural Chemicals
25.
Heptachlor		 Insecticide Law Concerning the Examination and Regulation of Manufacture,etc., of Chemical Substances Class I in 1986, lapsed in 1975, Poisonous and Deleterious Substances Control Law, , POPs
26.
Heptachlor epoxide		 Heptachlor metabolite
27.
Malathion		 Insecticide Registered, Food Sanitation Law
28.
Methomyl		 Insecticide Registered, Poisonous and Deleterious Substances Control Law
29.
Methoxychlor		 Insecticide Lapsed in 1960
30.
Mirex		 Insecticide Unregistered in Japan, POPs
31.
Nitrofen		 Herbicide Lapsed in 1982
32.
Toxaphene (Camphechlor)		 Insecticide Unregistered in Japan, POPs
33.
Tributyltin		 Antifouling paints on ships,
antiseptic for fishnets		 Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substancesre TBTO: Class I, the remaining 13 substances: Class II TB in 1990, Harmful Substance Containing Household Products Control Law
34.
Triphenyltin		 Antifouling paints on ships,
antiseptic for fishnets		 Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class II in 1990, lapsed in 1990, Harmful Substance Containing Household Products Control Law
35.
Trifluralin		 Herbicide Registered
36.
Alkyl phenol (from C5 to C9) Nonyl phenol


Octyl phenol		 Raw material for surface-active agents/decomposition product Raw material for surface-active agents/decomposition product Marine Pollution Prevention Law
37.
Bisphenol A		 Raw material for resins Food Sanitation Law
38.
Di-(2-ethylhexyl)phthalate		 Plasticizer for plastics Monitoring substances in water environment
39.
Butyl benzyl phthalate		 Plasticizer for plastics Marine Pollution Prevention Law
40.
Di-n-butyl phthalate		 Plasticizer for plastics Marine Pollution Prevention Law
41.
Dicyclohexyl phthalate		 Plasticizer for plastics
42.
Diethyl phthalate		 Plasticizer for plastics Marine Pollution Prevention Law
43.
Benzo(a)pyrene		 (Unintended product)
44.
Dichlorophenol		 Dye intermediate Marine Pollution Prevention Law
45.
Diethylhexyl adipate		 Plasticizer for plastics Marine Pollution Prevention Law
46.
Benzophenone		 Synthetic raw materials for medical products, perfume, etc.
47.
4-Nitrotoluene		 2,4-dinitrotoluene intermediate Marine Pollution Prevention Law
48.
Octachlorostyrene		 (By-product of organic chlorine compound)
49.
Aldicarb		 Insecticide Unregistered in Japan
50.
Benomyl		 Bactericide Registered
51.
Kepone (Chlordecone)		 Insecticide Unregistered in Japan
52.
Manzeb (Mancozeb)		 Bactericide Registered
53.
Maneb		 Bactericide Registered
54.
Metiram		 Bactericide Lapsed in 1975
55.
Metribuzin		 Herbicide Registered, Food Sanitation Law
56.
Cypermethrin		 Insecticide Registered, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
57.
Esfenvalerate		 Insecticide Registered, Poisonous and Deleterious Substances Control Law
58.
Fenvalerate		 Insecticide Registered, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
59.
Permethrin		 Insecticide Registered, Food Sanitation Law
60.
Vinclozololin		 Bactericide Lapsed in 1998
61. Zineb Bactericide Registered
62.
Ziram		 Bactericide Registered
63.
Dipentyl phthalate		 Not produced in Japan
64.
Dihexyl phthalate		 Not produced in Japan
65.
Dipropyl phthalate		 Not produced in Japan
66.
Styrens		 Non-reacting substance of styrene-rubber plastic
67.
n-Butylbenzene		 Synthesis intermediate, for liquid crystal manufacture
NOTE
(1) Besides the above substances, cadmium, lead, and mercury are also suspected of having endocrine disrupting effects.
(2) In the environmental investigation column, (2 indicates that the substance has been detected and i indicates that it has not been detected. Substances with no mark have not been investigated.
(3) The laws described in the restrictions column indicate that the substance is subject to restrictions under such laws.
(4) "Registered", "lapsed", "unregistered in Japan," "Soil-persistent Agricultural Chemicals," "Crop-persistent Agricultural Chemicals," "Water-pollutant Agricultural Chemicals" are based on the Agricultural Chemicals Regulation Law.
(5) POPs are residual organic pollutants specified in the "World Action Plan Concerning the Protection of the Marine Environment by Conducting Environmental Protection Activities on Land".