Health & Chemicals

Japan HPV Challenge Program

The Ministry of Health, Labor and Welfare (MHLW), the Ministry of Economy, Trade and Industry (METI) and the Ministry of the Environment (MOE) of the Japanese Government announced, on June 1, 2005, a program to facilitate safety information collection of High Production Volume (HPV) chemicals. The program named “Japan HPV Challenge Program” is a joint initiative of the Japanese Government and industry, especially manufacturers and importers of the chemicals in Japan.
Key features of the program are shown below.

  • The target chemicals of the program are organic substances produced or imported in Japan over 1,000 ton per year. The program, however, does not exclude low production volumes chemicals in particular, for effective development and application of category approach.
  • Information will be gathered in accordance with OECD SIDS initial assessment.
  • The program will avoid duplication with the past, ongoing and planned safety information collection activities including OECD-HPV and the US Challenge Program. The program will make efforts to contribute to the OECD-HPV wherever possible.
  • Industry volunteers to sponsor information gathering of the listed chemicals. Sponsors for each chemical will gather safety information. Forming a consortium is recommended for efficient use of resources and avoidance of duplicative testing. Proposals to employ category approach are encouraged.
  • It is anticipated that collection of the information on HPV chemicals in Japan (excluding those which are subject to information collection under OECD-HPV Chemicals Programme or other initiatives) be accomplished by the end of Japanese fiscal year 2008.
  • Collected safety information will be available to the public through the Internet.
  • The list of target substances may be reviewed when appropriate.

The latest list of the target chemicals of Japan HPV Challenge Program[PDF] (as of May 2007)
The list provides information on chemicals such as CAS number, chemical name (both English and Japanese) and status of international information gathering (only in Japanese). Thus the chemicals for which the column at the end right side is blank are expected to be sponsored by companies in the Japan HPV Challenge Program.

Outline of Japan HPV Challenge Program[PDF] (March 2007)

Current situation of Japan HPV Challenge Program (as of May 2007)
Total number of the target chemicals: 652
Of which 140 chemicals are expected to be sponsored by companies
Of which 80 chemicals has sponsored by companies

The Japan Challenge Program Final Report[PDF] (September 2013)

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