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31,056,000 Yen (FY 1998; 13,032,000 Yen)
Ecological and genetic interactions between Eupatorium makinoi and geminiviruses were examined. Virus infection decreased growth rate and survivorship under controlled condition and was a major mortality factor in the field. While geminiviruses were genetically highly variable in the host-range gene, suggesting high ability of adaptive changes against host's resistance, E. makinoi had genetically variable resistance genes. We investigated prevalence of canine distemper virus (CDV) infection in Japanese dogs genetically, seroepidemiologically and histopathologically. Japanese racoon dogs were naturally infected with recent type of CDV which are prevalent in dogs. Aquatic mammals on Japanese coast, in Caspian Sea and in Lake Baikal were also naturally infected with morbillivirus in recent years.
viral disease, resistance, genetic variation, canine distemper virus, morbillivirus