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A-4.4 Epidemiological and experimental studies for the effects of UV-B irradiation on the immune response and infectious diseases

[Contact Person]

Kiichi Yamamoto, Senior researcher
Department of Virology I,
The National Institute of Infectious Diseases,
The Ministry of Health and Welfarec,
1-23-1 Toyama, Shinjuku-ku, Tokyo 162, Japan
Tel:+81-3-5285-1111, Fax:+81-3-5285-1188

Total Budget for FY1996-1998

18,001,000 Yen (FY 1998; 6,000,000)

[A] A trial introducing epidemiological method in the fields of immune response and infectious diseases.

[Abstract]

In this study, to clarify the effect of UV-B exposure from sunlight on immune responses epidemiologically, we analyzed the data of tuberculin-reaction tests (TRT) on infants and students. The TRT-positive rate notably declined from north to south, dependent on latitude. This trend was reversely relative to increasing UV-B irradiation from the north to the south of Japan.

[Key Words]

Tuberculin-reaction test (TRT), latitude, UV-B exposure level, negative correlation