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[B-13.1.1 Study on Physiological Effects of Heat Stress]

[Contact Person]

Mitsuru Ando
Chief Research Scientist, Technology
Development Health Risk Research Team,
Regional Environment Division National
Institute for Environmental Studies,
Environment Agency
Onogawa 16-2, Tsukuba, Ibaraki, 305 Japan
Tel:+81-298-51-6111(Ext.522), Fax:+81-298-51-4732

[Total Budget for FY1990-1992]

25,361,000 Yen

[Abstract]

　Global warming has potential impacts on human health during extreme high temperature in summer. The epidemiological results showed that hyperthermia caused by heat stress induced many heat stroke patients in Nanjing, China.
　Since heat stress caused an increase in morbidity and mortality, oxygen radical damages in hyperthermia were studied. Since lipid peroxidation was greatly induced in liver, hyperthermia greatly developed hypertrophy and vacuolized degeneration in hepatic cells. Protective enzymes, such as glutathione peroxidase activities were induced in hyperthermia. Heat stress also affected central nervous systems and changed the sleeping behaviour.

[Key Words]

Health Risk, Heat Stress, Heat Wave, Radical Damage, Central Nervous System