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BOOKLET to Provide Basic Information Regarding Health Effects of Radiation (3rd edition)

Survey of Children of Childhood Cancer Survivors

Survey of Children of Childhood Cancer Survivors_Figure

This is the results of the survey of children of childhood cancer survivors in the United States and Canada. As in the case of the surveys targeting children of atomic bomb survivors, excess incidence of chromosome aberrations, Mendelian disorders and malformation was not observed. Based on the study on heritable effects among laboratory mice, the International Commission on Radiological Protection (ICRP) estimates the doubling dose for hereditary disorders to be 1 Gy. However, these survey results do not show any increases in chromosome aberrations and Mendelian disorders expected from the average gonadal doses.

 

Source:

  • D.M. Green et al.: J. Clin. Oncol. 27: 2374-2381, 2009.
    • Included in this reference material on February 28, 2018
    • Updated on March 31, 2019
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