Health & Chemicals

Strategic Programs on Environmental Endocrine Disruptors '98 (SPEED '98) - Table-3

Table-3: Chemicals Suspected of Having Endocrine Disrupting Effects

SubstancesEnvironmental InvestigationUseRestrictions
1.
Dioxins and furans
(Unintended product) Air Pollution Law, Waste Disposal and Public Cleaning Law, POPs
2.
Polychlorinated biphenyl
(PCB)
Heat medium, non-carbon paper, electric product Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1974, stopped production in 1972, Water Pollution Control Law, Marine Pollution Prevention Law, Waste Disposal and Public Cleaning Law, Environmental Quality Standards for Groundwater, Soil Pollution, and Water Pollutants, POPs
3.
Polybromobiphenyl (PBB)
Fire retardant
4.
Hexachlorobenzene (HCB)
Bactericide, organic synthetic raw material Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1979, unregistered in Japan, POPs
5.
Pentachlorophenol (PCP)
Antiseptic, herbicide,
bactericide
Lapsed in 1990, Water-pollutant Agricultural Chemicals, Poisonous and Deleterious Substances Control Law
6.
2,4,5-Trichlorophenoxyacetic acid
Herbicide Lapsed in 1975, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
7.
2,4-Dichlorophenoxyacetic acid
Herbicide Registered
8.
Amitrole
Herbicide, disperse dye,
hardener for resins
Lapsed in 1975, Food Sanitation Law
9.
Atrazine
Herbicide Registered
10.
Alachlor
Herbicide Registered, Marine Pollution Prevention Law
11.
Simazine (CAT)
Herbicide Registered, Water Pollution Control Law, Environmental Quality Standards for Groundwater, Soil Pollution, and Water Pollutants, Waste Disposal and Public Cleaning Law, Waterworks Law
12.
Hexachlorocyclohexane,
Ethyl parathion
Insecticide, Hexachlorocyclohexane lapsed and banned sales in 1971, ethyl parathion lapsed in 1972
13.
Carbaryl
Insecticide Registered, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
14.
Chlordane
Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1968, Poisonous and Deleterious Substances Control Law, POPs
15.
Oxychlordane
Chlordane metabolite
16.
trans-Nonachlor
Insecticide Nonachlor unregistered in Japan, heptachlor lapsed in 1972
17.
1,2-dibromo- 3-chloropropane
Insecticide Lapsed in 1980
18.
DDT
Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed and banned sales in 1971, Food Sanitation Law, POPs
19.
DDE and DDD
Insecticide (DDT metabolite) Unregistered in Japan
20.
Kelthane (Dicofol)
Acaricide Registered, Food Sanitation Law
21.
Aldrin
Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1975, Soil-persistent Agricultural Chemicals, Poisonous and Deleterious Substances Control Law, POPs
22.
Endrin
Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1975, Crop-persistent Agricultural Chemicals, Poisonous and Deleterious Substances Control Law, Food Sanitation Law, POPs
23.
Dieldrin
Insecticide Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class I in 1981, lapsed in 1975, Soil-persistent Agricultural Chemicals, Poisonous and Deleterious Substances Control Law, Food Sanitation Law, Harmful Substance Containing Household Products Control Law, POPs
24.
Endosulfan (Benzoepin)
Insecticide Poisonous and Deleterious Substances Control Law, Water-pollutant Agricultural Chemicals
25.
Heptachlor
Insecticide Law Concerning the Examination and Regulation of Manufacture,etc., of Chemical Substances Class I in 1986, lapsed in 1975, Poisonous and Deleterious Substances Control Law, , POPs
26.
Heptachlor epoxide
Heptachlor metabolite
27.
Malathion
Insecticide Registered, Food Sanitation Law
28.
Methomyl
Insecticide Registered, Poisonous and Deleterious Substances Control Law
29.
Methoxychlor
Insecticide Lapsed in 1960
30.
Mirex
Insecticide Unregistered in Japan, POPs
31.
Nitrofen
Herbicide Lapsed in 1982
32.
Toxaphene (Camphechlor)
Insecticide Unregistered in Japan, POPs
33.
Tributyltin
Antifouling paints on ships,
antiseptic for fishnets
Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substancesre TBTO: Class I, the remaining 13 substances: Class II TB in 1990, Harmful Substance Containing Household Products Control Law
34.
Triphenyltin
Antifouling paints on ships,
antiseptic for fishnets
Law Concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances Class II in 1990, lapsed in 1990, Harmful Substance Containing Household Products Control Law
35.
Trifluralin
Herbicide Registered
36.
Alkyl phenol (from C5 to C9) Nonyl phenol


Octyl phenol
Raw material for surface-active agents/decomposition product Raw material for surface-active agents/decomposition product Marine Pollution Prevention Law
37.
Bisphenol A
Raw material for resins Food Sanitation Law
38.
Di-(2-ethylhexyl)phthalate
Plasticizer for plastics Monitoring substances in water environment
39.
Butyl benzyl phthalate
Plasticizer for plastics Marine Pollution Prevention Law
40.
Di-n-butyl phthalate
Plasticizer for plastics Marine Pollution Prevention Law
41.
Dicyclohexyl phthalate
Plasticizer for plastics
42.
Diethyl phthalate
Plasticizer for plastics Marine Pollution Prevention Law
43.
Benzo(a)pyrene
(Unintended product)
44.
Dichlorophenol
Dye intermediate Marine Pollution Prevention Law
45.
Diethylhexyl adipate
Plasticizer for plastics Marine Pollution Prevention Law
46.
Benzophenone
Synthetic raw materials for medical products, perfume, etc.
47.
4-Nitrotoluene
2,4-dinitrotoluene intermediate Marine Pollution Prevention Law
48.
Octachlorostyrene
(By-product of organic chlorine compound)
49.
Aldicarb
Insecticide Unregistered in Japan
50.
Benomyl
Bactericide Registered
51.
Kepone (Chlordecone)
Insecticide Unregistered in Japan
52.
Manzeb (Mancozeb)
Bactericide Registered
53.
Maneb
Bactericide Registered
54.
Metiram
Bactericide Lapsed in 1975
55.
Metribuzin
Herbicide Registered, Food Sanitation Law
56.
Cypermethrin
Insecticide Registered, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
57.
Esfenvalerate
Insecticide Registered, Poisonous and Deleterious Substances Control Law
58.
Fenvalerate
Insecticide Registered, Poisonous and Deleterious Substances Control Law, Food Sanitation Law
59.
Permethrin
Insecticide Registered, Food Sanitation Law
60.
Vinclozololin
Bactericide Lapsed in 1998
61. Zineb Bactericide Registered
62.
Ziram
Bactericide Registered
63.
Dipentyl phthalate
Not produced in Japan
64.
Dihexyl phthalate
Not produced in Japan
65.
Dipropyl phthalate
Not produced in Japan
66.
Styrens
Non-reacting substance of styrene-rubber plastic
67.
n-Butylbenzene
Synthesis intermediate, for liquid crystal manufacture
NOTE
(1) Besides the above substances, cadmium, lead, and mercury are also suspected of having endocrine disrupting effects.
(2) In the environmental investigation column, (2 indicates that the substance has been detected and i indicates that it has not been detected. Substances with no mark have not been investigated.
(3) The laws described in the restrictions column indicate that the substance is subject to restrictions under such laws.
(4) "Registered", "lapsed", "unregistered in Japan," "Soil-persistent Agricultural Chemicals," "Crop-persistent Agricultural Chemicals," "Water-pollutant Agricultural Chemicals" are based on the Agricultural Chemicals Regulation Law.
(5) POPs are residual organic pollutants specified in the "World Action Plan Concerning the Protection of the Marine Environment by Conducting Environmental Protection Activities on Land".
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