Health & Chemicals

Strategic Programs on Environmental Endocrine Disruptors '98 (SPEED '98) - Table-1

Table-1: The main functions of hormones in humans and the diseases which can result from the overproduction and shortage of hormones

HormonesSitesThe main functions (control functions)Main diseases
OversecretionShortage of secretion/ receptor abnormality
growth hormone pituitary gland acceleration of growth giantism,
acromegaly
dwarfism
thyroid hormone thyroid gland acceleration of metabolism,
control of intelligence and growth
hyperthyroidism
(Basedow's disease)
hypothyroidism
insulin pancreas decrease of blood sugar hypoglycemia hyperglycemia (diabetes)
adrenal cortical
hormone
adrenal gland control of metabolism,
immune, etc.
stress response
Cushing's syndrome Addison's disease
estrogen (female sex
hormone)
ovary feminization
(menstruation, mammary gland),
development of ova,
ovulation
endometriosis,
vaginal carcinoma,
breast cancer,
metrorrhagia
developmental abnormality of female genitalia,
menstrual disorder
androgen
(male sex hormone)
testis virilization,
development of testis,
spermatogenesis
premature development of secondary sex characteristics developmental abnormality of male genitalia,
azoospermia,
testicular feminization syndrome
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