環境省保健・化学物質対策化学物質の内分泌かく乱作用国際シンポジウム

第8回化学物質の内分泌かく乱作用に関する国際シンポジウム 発表資料

Monday, December 5, 2005 (Program for Experts)

9:30-11:45

Session 1 Some Considerations on Epidemiological Studies

Coordinator: Chiharu Tohyama (Graduate School of Medicine, The University of Tokyo, Japan)

Difficulties in Conducting an Epidemiological Study for Endocrine Disrupting Chemicals
Seiichiro Yamamoto (National Cancer Center, Japan)
Evaluation of Endocrine Disrupters in Women and Children: Lessons from the CHAMACOS and Seveso Women’s Health Studies
Brenda Eskenazi (University of California, Berkeley, U.S.A)
Interpreting the Significance of Small Effect Sizes in Epidemiological Studies
David C. Bellinger (Harvard Medical School / Harvard School of Public Health, U.S.A.)
11:45 Lunch
13:00-15:15

Session 2 Risk Communication: Present Status and Future Directions

Coordinator: Iwao Uchiyama (Graduate School of Engineering, Kyoto University, Japan)

A systematic Guide for Risk Communication with Special Focus on Risk Characterization, Risk Amplification, and Precaution
Peter M. Wiedemann (Research Centre Juelich, Germany)
Risk Communication and Mass Media
Shigeyuki Koide (The Yomiuri Shimbun, Japan)
The Current Status of Risk Communication in Japan
Toshiko Kikkawa (Keio University, Japan)
15:15 Break
15:30-17:45

Session 3 Community and Ecosystem Level Assessment of Human Impacts

Coordinator: Takayuki Hanazato (Shinshu University, Japan)

Impacts of Endocrine Disruption on Roach, Rutilus Rutilus, Populations Living in UK Rivers
Charles R. Tyler (University of Exeter, U.K.)
40 Years of Change on Iriomote Island
Shigeki Yasuma (The Hiraoka Environmental Science Laboratory, Japan)
Biological Interactions: Important Factors in Structuring Organic Communities and Controlling the Pesticide Impact on Ecosystems
Takayuki Hanazato (Shinshu University, Japan)

Tuesday, December 6, 2005 (Program for Experts)

9:30-11:45

Session 4 New Approaches to Mechanistic Understanding of Endocrine Disrupters

Coordinator: Hajime Watanabe (National Institutes of Natural Sciences, Japan)

Effects of Persistent Organic Pollutants on mRNA Expression in Avian Neuronal and Hepatic Cells Using FRAP-PCR and SAGE
Sean W. Kennedy (National Wildlife Research Centre, Canada)
Germ Cell Apoptosis in Rat Testis is Induced by Oxidative Stress via Oral Administration of di (2-ethyl-hexyl) phthalate, and is Significantly Prevented by Treatment of Antioxidant Vitamins or Special Six-Carbon Monosaccharides
Masaaki Tokuda (Kagawa University, Japan)
Effects of Estrogenic Chemicals Estimated by Gene Expression Profile
Hajime Watanabe (National Institutes of National Sciences, Japan)
11:45 Lunch
13:00-15:15

Session 5 Development of Testing Methods for Endocrine Disruption

Coordinator: Taisen Iguchi (National Institutes of Natural Sciences, Japan)

The Validation Management Group for Non-Animal Testing (VMG-NA) of the OECD Task Force for Endocrine Disputing Testing and Assessment (EDTA)
Patric S. Amcoff (Organization for Economic Cooperation and Development (OECD))
資料 1/2 [PDF 300KB] 2/2  [PDF 186KB]
Development of OECD Test Guidelines for Endocrine Active Substances in Environmental Species
Anne Gourmelon (Organization for Economic Cooperation and Development (OECD))
Environmental Risk Assessment of Endocrine Disrupters: Status and Needs of Biomarkers
Thomas H. Hutchinson (AstraZeneca R&D, Sweden)
15:15 Break
15:30-17:45

Session 6 Current Initiatives on Risk Assessment of Chemicals

Coordinator: Hiroaki Shiraishi (National Institute for Environmental Studies, Japan)

Roadmap for Implementing the USEPA Endocrine Disrupter Screening Program
Karen Whitby (U.S. Environmental Protection Agency, U.S.A.)
Developing Approaches to Chemicals Management - A UK View
Michael J. Roberts (Department for Environment, Food and Rural Affairs, U.K.)
Japan’s Approach for the Prevention of Environmental Pollution Caused by Chemicals
Satoru Morishita (Ministry of the Environment, Japan)

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