| Development of Test
Methods with Medaka to Detect Endocrine
Disrupting Chemicals |
|
| Opening Address (9:30-9:45) Abstract [Japanese OS/English OS] |
| I. Kazuhiko Adachi: Director of Environmental
Health and Safety Division, Ministry of the
Environment, Japan |
| II. Taisen Iguchi: Center for Integrative
Bioscience, Okazaki National Research Institutes,
Japan |
| III. Anne Gourmelon: Environmental Health
and Safety Division, OECD |
|
| Session I Each Fish's Activity of Evaluation
of Endocrine Disrupting Chemicals [Japanese OS/English OS] |
| (Chairperson: Anne Gourmelon) |
| |
9:45-10:00 |
Medaka (Taisen Iguchi: Okazaki National Research
Institutes) |
| |
10:00-10:45 |
Zebra fish (Thomas Braunbeck: Heidelberg
University) |
| |
10:45-11:30 |
Fathead minnow (Karen Thorpe: University
of Exeter/AstraZeneca) |
|
| Special Lecture Sex Determination and Gonadal
Sex Differentiation in Fish (13:00-14:00)
[Japanese OS/English OS] |
| Yoshitaka Nagahama: National Institute for
Basic Biology (Chairperson: Taisen Iguchi) |
|
| Session II Endocrine Disrupting Effects and
Test Methods with Medaka [Japanese OS/English OS] |
| Part I |
(Chairperson: Taisen Iguchi) |
| |
14:00-14:25 |
Availability of Receptor Binding Assay for
Screening of Endocrine Disrupting Chemicals
(Makoto Nakai: CERI, Japan) |
| |
14:25-14:55 |
Endocrine Disrupting Effects and Testing
Methods with Medaka (Masanori Seki: CERI,
Japan) |
| |
14:55-15:25 |
Partial Life-cycle Test and Full Life-cycle
Test in Medaka (Hirofumi Yokota: CERI, Japan) |
| Part II |
(Chairperson: Koji Arizono) |
| |
15:40-16:05 |
Relationship Between Vitellogenin and Genetic
Sex in Medaka Partial Life-cycle Test with
the Novel Sex Determining Gene, DMY (Tatsuo
Abe: CERI, Japan) |
| |
16:05-16:30 |
Transgenic See-Through Medaka for Monitoring
Chemical Substances in Aquatic Environments
(Yuko Wakamatsu: Nagoya University, Japan
& Masato Kinoshita: Kyoto University,
Japan) |
| |
16:30-16:55 |
Feeding and Preparing Endocrine-Disrupting
Chemicals Free Food (Koji. Arizono: Prefectural
University of Kumamoto, Japan) |
|
| |
16:55-17:00 |
Other information, medaka report (Chisumi
Eto: CERI, Japan) [Japanese OS/English OS] |
|
| Closing |
17:00 |
Kenjiro Ozato: Emeritus Professor of Nagoya
University, Japan [Japanese OS/English OS] |
|
| February 28, Friday |
| Technical Meeting and Strategy on Phase 1
Test Session I. OECD's Framework and Recent
Studies with Three Fish Species [Abstract
is not prepared - program only -] |
|
| Session I OECD's Framework and Recent Studies
with Three Fish Specie (Chairpersons: Taisen
Iguchi, Rodney D. Johnson and Anne Gourmelon) |
| 10:00-11:40 |
|
Report on the Results of Positive Controls,
such as EE2, E2 and MT etc. with three Fish
Species |
| |
10:00-10:30 |
Medaka (Masanobu Maeda: CERI, Japan) |
| |
10:30-11:00 |
Zebrafish (Gitte Petersen: DHI Water and
Environment) |
| |
11:00-11:30 |
Fathead minnow (Rodney Johnson: EPA, USA) |
| |
11:30-11:40 |
Discussion |
|
| Session II Sensitivity and/or Variance of
Parameters such as Vitellogenin and Gonad
Histology for Three Fish Species (Chairpersons:
Taisen Iguchi, Rodney D. Johnson and Anne
Gourmelon) |
| Part
I |
|
|
| 12:40-14:10
|
|
Vitellogenin (for methodology, antibody and
standard) |
| |
12:40-13:00
|
Medaka (Norihisa Tatarazako: National Institute
for Environmental Studies, Japan) |
| |
13:00-13:20
|
Zebrafish
(Thomas Braunbeck: Heidelberg University) |
| |
13:20-13:40
|
Fathead
minnow (Karen Thorpe; University of Exeter/AstraZeneca) |
| |
13:40-14:10
|
Discussion |
| Part
II |
|
|
| 14:25-16:05
|
|
Gonadal Historogy (for methodology and endpoints
available for each fish including secondary
sex characteristics) |
| |
14:25-14:45 |
Medaka (Masanori Seki: CERI, Japan) |
| |
14:45-15:05 |
Zebrafish (Leif Norrgren: Swedish University
of Agricultural Sciences) |
| |
15:05-15:25 |
Fathead minnow (Rodney Johnson: EPA, USA) |
| |
15:25-16:05 |
Discussion |
| Part III |
|
|
| |
16:05-16:30 |
Draft Protocol of Phase 1 Test and Other
Issues |
| |
|
General Discussion |
| 16:30 |
|
Closing |