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環境省保健・化学物質対策科学的知見の充実及び環境リスク評価の推進化学物質の内分泌かく乱作用に関するホームページ資料集・リンク専門家向けデータベース:メダカアトラス トップ >3.Atlas of Gonadal Histopathology in Medaka Exposed to Endocrine Disruptors (3)

「資料集・リンク」

資料集・リンク
専門家向けデータベース

「専門家向けデータベース」

Atlas of Medaka Gonadal Histology

by MOE and Chemicals Evaluation and Research Institute, Japan (CERI)

Atlas of Gonadal Histopathology in Medaka Exposed to Endocrine Disruptors

Effect of estrogen exposure

Testis-ova

Testis-ova from a fish exposed to 958 µg/L of flutamide from fertilized egg to 60-d posthatch (Bouin, H&E).
O: oocyte, Sc: spermatocyte, Sz: spermatozoa.
Single oocyte exists within the testicular tissue. It is not clear that what mechanisms have been involved in the induction of testis-ova when exposed to anti-androgen.

Testis-ova

Ovary

Ovary from a fish exposed to 958 µg/L of flutamide from fertilized egg to 60-d (Bouin, H&E).
No effects are observed.

Ovary