「資料集・リンク」
「専門家向けデータベース」
by MOE and Chemicals Evaluation and Research Institute, Japan (CERI)
Medaka (Oryzias latipes) has been widely used as laboratory animal in various fields in biology. Its relatively short life cycle, capacity to reproduce, and ease of breeding are chiefly responsible for its popularity. In addition, medaka has been commonly used as test species for ecotoxicity tests. Standardized acute (OECD, 1992), prolonged (OECD, 1984) and early-life stage (OECD, 1992) toxicity have been developed for assessment, Medaka also is a suitable test organism for investigations of sex reversal and intersex in fish because this species is characterized as a differentiated gonochorist.
We provide here a basic data of normal development of testis and ovary in development of medaka as well as growth, secondary sexual characteristics and vitellogenin synthesis. In addition, we show several images of gonadal tissues in the fish exposed to model endocrine disrupting chemicals. We hope that these data will be used for the further study of ecotoxicity and endocrine disruptors testing in medaka.